Late-Onset Lupus Nephritis: Clinical-Epidemiological, Histological, Prognostic, and Therapeutic Implications: A Single-Center Experience from Northeastern Spain

Late-onset LN is often accompanied by other systemic autoimmune diseases such as Sjögren's and antiphospholipid syndrome. These patients have major cardiovascular comorbidities, poor estimated glomerular filtration rate (eGFR) at diagnosis, and increased chronicity index in histology. A tailored approach in this fragile population in order to avoid unnecessary immunosuppression is of critical interest.