Repurposing tafenoquine as a potent antifungal agent against <i>Candida haemulonii sensu stricto</i>
The findings of this study highlight tafenoquine's potential as a promising candidate for antifungal drug repurposing, especially against C. haemulonii sensu stricto. Its effectiveness in inhibiting fungal growth and biofilm formation underscores its viability for further clinical development as a novel antifungal therapy.
Authors
- Fabíola Lucini (ORCID: https://orcid.org/0000-0001-6658-4043)
- Gabriela Fernandes Silva (ORCID: https://orcid.org/0000-0002-0699-2640)
- Simone Simionatto (ORCID: https://orcid.org/0000-0003-2367-0915)
- Luana Rossato (ORCID: https://orcid.org/0000-0002-6115-3313)
- Larissa Rodrigues Pimentel
Institutions
- Universidade Federal da Grande Dourados (BR)
Publication Details
- Journal
- Journal of Antimicrobial Chemotherapy
- Published
- 2025-02-24
- DOI
- https://doi.org/10.1093/jac/dkaf054
- Citations
- 1
- Primary Topic
- Antifungal resistance and susceptibility
- Type
- article
- Field-Weighted Citation Impact
- 1.40
Funders
- Conselho Nacional de Desenvolvimento Científico e Tecnológico
- Fundação de Apoio ao Desenvolvimento do Ensino, Ciência e Tecnologia do Estado de Mato Grosso do Sul