FBF1 maintains stem cell-like properties in breast cancer via PI3K/AKT/SOX2 axis
Collectively, we identified a potential CSCs regulator and suggested a novel mechanism by which FBF1 governs cancer cell stemness. This study thus introduces an effective target for the diagnosis and treatment of breast cancer.
Authors
- Ang Liang
- Yunwei Lou (ORCID: https://orcid.org/0000-0001-8296-0395)
- Yuan Ma (ORCID: https://orcid.org/0000-0002-7846-4863)
- Hui Liu (ORCID: https://orcid.org/0000-0003-0287-7423)
- Shuang Li (ORCID: https://orcid.org/0000-0002-6828-5925)
- Hui Wang (ORCID: https://orcid.org/0000-0002-2454-3814)
- Chunlei Guo (ORCID: https://orcid.org/0009-0003-6085-7049)
- Jiaqing Liu (ORCID: https://orcid.org/0009-0003-8777-8375)
Institutions
- Henan Medical University (CN)
Publication Details
- Journal
- Stem Cell Research & Therapy
- Published
- 2025-02-23
- DOI
- https://doi.org/10.1186/s13287-025-04194-9
- Citations
- 3
- Primary Topic
- Fibroblast Growth Factor Research
- Type
- article
- Field-Weighted Citation Impact
- 2.42
Funders
- National Natural Science Foundation of China
- Higher Education Discipline Innovation Project