Autologous iPSC- and MSC-derived chondrocyte implants for cartilage repair in a miniature pig model
Our findings contribute to filling the knowledge gap regarding the use of autologous iPSC derivatives for cartilage repair in a translational animal model. Moreover, these results highlight their potential as a safe and effective therapeutic strategy.
Authors
- Brett Nemke (ORCID: https://orcid.org/0000-0003-0329-1387)
- Athillesh Sivapatham
- Wan‐Ju Li (ORCID: https://orcid.org/0000-0002-6579-8063)
- Hongli Jiao (ORCID: https://orcid.org/0000-0001-8005-8496)
- Ellen M. Leiferman
- Ming‐Song Lee (ORCID: https://orcid.org/0000-0001-7660-1900)
- Matthew Leiferman
- Yan Lu
- Eric Chang‐Yi Lin (ORCID: https://orcid.org/0000-0003-0118-0448)
- Mark D. Markel
Institutions
- University of Wisconsin–Madison (US)
Publication Details
- Journal
- Stem Cell Research & Therapy
- Published
- 2025-02-23
- DOI
- https://doi.org/10.1186/s13287-025-04215-7
- Citations
- 12
- Primary Topic
- Osteoarthritis Treatment and Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 18.35
Funders
- National Institute of Arthritis and Musculoskeletal and Skin Diseases