Nec-1 regulates phenotypic transformation of heat stroke-induced vascular smooth muscle cells by inhibiting RIPK1
HS induces abnormal phenotypic transformation and necroptosis in VSMCs. Necrostatin-1 can improve necroptosis and maintain the contractile phenotype of VSMCs. This study can provide new insights into cardiovascular damage caused by high temperatures.
Authors
- Ling Hou (ORCID: https://orcid.org/0000-0003-2596-9953)
- Le Mu (ORCID: https://orcid.org/0009-0000-6467-3368)
- Shujing Xue
- Guanghua Li (ORCID: https://orcid.org/0000-0001-9977-0547)
- Xiaomin Wu (ORCID: https://orcid.org/0000-0003-1783-4143)
- Tuo Wei (ORCID: https://orcid.org/0000-0002-2823-9721)
Institutions
- Ningxia Medical University (CN)
- The Fourth People's Hospital of Ningxia Hui Autonomous Region (CN)
Publication Details
- Journal
- International Journal of Hyperthermia
- Published
- 2025-02-23
- DOI
- https://doi.org/10.1080/02656736.2025.2463477
- Citations
- 4
- Primary Topic
- Heat shock proteins research
- Type
- article
- Field-Weighted Citation Impact
- 3.22
Funders
- Natural Science Foundation of Ningxia Province