Development of iPSC-derived FIX-secreting hepatocyte sheet as a novel treatment tool for hemophilia B treatment
The engineered FIX-secreting cell sheets fabricated from functionally improved iPSCs with practical cell delivery tools could be a promising tool for clinically treating Hemophilia B.
Authors
- Delger Bayarsaikhan
- Govigerel Bayarsaikhan (ORCID: https://orcid.org/0000-0001-7934-038X)
- Kyung-Sook Kim (ORCID: https://orcid.org/0000-0002-0580-3510)
- Jaesuk Lee (ORCID: https://orcid.org/0000-0002-6063-4051)
- Bong‐Hee Lee
- Teruo Okano
Institutions
- Gachon University (KR)
- Seoul National University (KR)
- University of Utah (US)
- Tokyo Women's Medical University (JP)
Publication Details
- Journal
- Stem Cell Research & Therapy
- Published
- 2025-02-23
- DOI
- https://doi.org/10.1186/s13287-025-04195-8
- Citations
- 4
- Primary Topic
- CRISPR and Genetic Engineering
- Type
- article
- Field-Weighted Citation Impact
- 3.22