The Impact of TRX Exercises and Avodin Supplementation on Liver Enzyme levels in Patients with Rheumatoid Arthritis

Background & Aim:The increasing development of rheumatoid arthritis (RA) has led to the occurrence of other co-morbidities, including liver diseases.This research aimed to investigate the effect of TRX exercises with avodin supplementation on liver enzymes in patients with rheumatoid arthritis. Methods:The present study was an applied type of research, using a semi-experimental method.The statistical population consist of patients with rheumatoid arthritis, from which 40 patients were selected using a convenient sampling method.These patients were then divided into four groups (N=10): 1) exercise, 2) supplement, 3) exercise + supplement, and 4) control.Blood samples were taken from all subjects at the beginning and end of the study to measure serum levels of AST, ALT, ALP, ALB, and TP.The subjects then underwent a course of TRX exercises and avodin supplementation (3 sessions per week, for 8 weeks, with adosage of 300 mg/kg body weight).Data analysis was done by the ANOVA, Bonferroni's post hoc test, t-test with using SPSS version 27 software with a significance level of P<0.05. Results:The study showed a significant decrease in weight for the exercise-supplement group compared to both the control group (P=0.037) and the supplement group (P=0.021).Additionally, there was a significant decrease in liver enzymes AST, ALT, TP, and ALB in the exercise+supplement group compared to the control and supplement groups (P=0.001).Furthermore, there was a significant reduction in liver markers from pre-test to post-test in the exercise+supplement group (P=0.001). Conclusion:Taking avodin while performing TRX exercises can effectively control weight and improve liver indicators.This combination of interventions may also help prevent the development of liver diseases in individuals with RA.