Changes and prognostic significance of autonomic cardiac regulation during ageing
Almost all the HRV parameters decreased during ageing. Larger decrease of VLF(ln) and LF(ln) predicted total and CV-mortality after adjustments indicating that larger attenuation in cardiac autonomic regulation during ageing yields prognostic information. Of the baseline HRV parameters LF(ln) dichotomized and DFA1 had the strongest prognostic value on total and CV-mortality.
Authors
- Mikko P. Tulppo (ORCID: https://orcid.org/0000-0001-5598-9109)
- Antti O. Vuoti
- Heikki V. Huikuri (ORCID: https://orcid.org/0000-0001-8800-963X)
- Antti M. Kiviniemi (ORCID: https://orcid.org/0000-0002-1160-493X)
- Olavi Ukkola (ORCID: https://orcid.org/0000-0001-7414-2608)
- Juha S. Perkiömäki (ORCID: https://orcid.org/0000-0002-1157-3985)
- Juhani Junttila (ORCID: https://orcid.org/0000-0002-8896-1281)
- Elisa Karhumaa
Institutions
- Oulu University Hospital (FI)
- University of Oulu (FI)
Publication Details
- Journal
- Autonomic Neuroscience
- Published
- 2025-02-23
- DOI
- https://doi.org/10.1016/j.autneu.2025.103255
- Primary Topic
- Heart Rate Variability and Autonomic Control
- Type
- article
- Field-Weighted Citation Impact
- 0.00