Characterisation of MRGPRX2 <sup>+</sup> mast cells in irritable bowel syndrome
The MRGPRX2 pathway is functionally upregulated in the colon of patients with IBS, supporting its role in abdominal pain in IBS.
Authors
- Yasuhiro Tsukimi
- Hind Hussein (ORCID: https://orcid.org/0000-0001-6309-8242)
- Stuart M. Brierley (ORCID: https://orcid.org/0000-0002-2527-2905)
- Lisse Decraecker (ORCID: https://orcid.org/0000-0002-5366-1262)
- Jill Wykosky
- Runze Quan (ORCID: https://orcid.org/0000-0002-7536-4939)
- T. Gibson
- Mira M. Wouters (ORCID: https://orcid.org/0000-0002-3438-1919)
- Pieter Vanden Berghe (ORCID: https://orcid.org/0000-0002-0009-2094)
- Wendy J. Winchester
- Guy E. Boeckxstaens (ORCID: https://orcid.org/0000-0001-8267-5797)
- Nathalie Stakenborg (ORCID: https://orcid.org/0000-0002-6229-0045)
- Alexandre Denadai‐Souza (ORCID: https://orcid.org/0000-0003-0385-1321)
- Andrea Fanjul
- Gareth A. Hicks (ORCID: https://orcid.org/0000-0001-5106-757X)
- Elisabetta De Marco (ORCID: https://orcid.org/0000-0002-5875-5313)
- Samuel Van Remoortel (ORCID: https://orcid.org/0000-0001-8425-5657)
- Maria Francesca Viola (ORCID: https://orcid.org/0000-0003-0660-9506)
- Sonia Garcia‐Caraballo (ORCID: https://orcid.org/0000-0001-5038-0820)
- Zheng Wang
- Maria Clara Sartório Estevez
Institutions
- South Australian Health and Medical Research Institute (AU)
- Takeda (Japan) (JP)
- The University of Adelaide (AU)
- KU Leuven (BE)
Publication Details
- Journal
- Gut
- Published
- 2025-02-23
- DOI
- https://doi.org/10.1136/gutjnl-2024-334037
- Citations
- 9
- Primary Topic
- Gastrointestinal motility and disorders
- Type
- article
- Field-Weighted Citation Impact
- 16.30
Funders
- Hercules Foundation
- Fonds Wetenschappelijk Onderzoek
- KU Leuven
- National Health and Medical Research Council
- Chinese Government Scholarship