Chemical analysis and biological activity of crude extracts obtained from leaves of <i>Passiflora foetida</i> (Subg. <i>Passiflora</i> ) and <i>Passiflora morifolia</i> (Subg. Decaloba)

The state of Bahia is an important producer of passion fruit, as well as emerging on the Brazilian national scene as a centre of origin and diversity of passionflowers. We aimed to identify bioactive compounds from <i>Passiflora morifolia</i> and <i>Passiflora foetida</i>. It was possible to identify three flavonoids in <i>P. foetida</i> and 8 molecules in <i>P. morifolia</i> using the HPLC-MS/MS technique. In total, 2 (two) compounds were detected, but it was not possible to identify them in the crude extract of <i>P. foetida</i> leaves. In <i>P. morifolia</i>, 1 (one) of the compounds was not identified, only detected. Regarding antiparasitic activity <i>P. morifolia</i> extract exhibits better activity against <i>Trypanosoma cruzi</i>, with inhibition of 50% of viable cells at a concentration of 125 µg.mL-1, while <i>P. foetida</i> performs better against cell growth of <i>Leishmania amazonensis</i> at a concentration of 500 µg.mL-1. These results highlight an interesting future path for these extracts in relation to their biological activity we can base proposals for bioproducts.