Fetal mice dermal mesenchymal stem cells promote wound healing by inducing M2 type macrophage polarization
FDMSCs effectively modulate macrophage polarization from M1 to M2, reduce inflammation, and enhance tissue repair, demonstrating their potential as an immunomodulatory strategy in wound healing. These findings highlight the promising therapeutic application of FDMSCs in managing chronic wounds.
Authors
- Zhenyu Xia (ORCID: https://orcid.org/0009-0006-8267-7841)
- Meiqi Lu
- Yi Wang (ORCID: https://orcid.org/0000-0003-3489-5183)
- Nian Shi (ORCID: https://orcid.org/0000-0002-3265-8646)
- Yaxin Deng (ORCID: https://orcid.org/0009-0005-7945-0120)
- Jie Zhao (ORCID: https://orcid.org/0009-0008-5457-8226)
- Duyin Jiang (ORCID: https://orcid.org/0000-0003-3233-1333)
- Xinglei Wang (ORCID: https://orcid.org/0000-0002-9894-5971)
- Yongjun Qi
Institutions
- Shandong University (CN)
- Second Hospital of Shandong University (CN)
Publication Details
- Journal
- World Journal of Stem Cells
- Published
- 2025-02-24
- DOI
- https://doi.org/10.4252/wjsc.v17.i2.101030
- Citations
- 9
- Primary Topic
- Mesenchymal stem cell research
- Type
- article
- Field-Weighted Citation Impact
- 14.63