Effect of adipose-derived stem cells exosomes cross-linked chitosan-αβ-glycerophosphate thermosensitive hydrogel on deep burn wounds
Our research demonstrates that the ASC-Exos cross-linked CS-αβ-GP hydrogel represents an advanced therapeutic approach for treating deep burn wounds. It has anti-inflammatory effects, promotes wound healing, and facilitates the transition of M1 macrophages to M2 macrophages by blocking the NF-κB pathway.
Authors
- Lei Xu (ORCID: https://orcid.org/0000-0001-7648-8100)
- Li Ren (ORCID: https://orcid.org/0000-0001-6481-0713)
- Wei Zhang
- Dan Liu (ORCID: https://orcid.org/0009-0008-7976-8042)
- Wenwen Li (ORCID: https://orcid.org/0000-0002-9036-4179)
- Chuan Han
- Hye Young Yun (ORCID: https://orcid.org/0009-0003-7534-5994)
Institutions
- Chengdu Military General Hospital (CN)
Publication Details
- Journal
- World Journal of Stem Cells
- Published
- 2025-02-24
- DOI
- https://doi.org/10.4252/wjsc.v17.i2.102091
- Citations
- 5
- Primary Topic
- Extracellular vesicles in disease
- Type
- article
- Field-Weighted Citation Impact
- 4.03