A rare case of macroamylasemia in a patient with SARS-CoV-2 infection

In this case report, we report about a 70-year-old hypertensive and asthmatic patient who was under inward treatment for mild COVID-19. He complained ofburning epigastric pain for one day and his elevated serum amylase level persisted months after the initial presentation. He underwent extensive investigations to exclude acute pancreatitis and other causes of high amylase levels. His amylase creatinine clearance ratio was 0.2%, his pre- polyethylene glycol(PEG) amylase concentration was 644 U/L, and his post-PEG amylase concentration was 10 U/L with a very low post-PEG recovery (1.55%). He was diagnosed with macroamylasemia.

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Publication Details

Journal
BMC Infectious Diseases
Published
2025-02-23
DOI
https://doi.org/10.1186/s12879-025-10642-x
Primary Topic
Pancreatitis Pathology and Treatment
Type
article
Field-Weighted Citation Impact
0.00
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article

A rare case of macroamylasemia in a patient with SARS-CoV-2 infection

Tilan Aponso, W. M. D. A. S. Wanninayake, N. M. M. Nawarathne
BMC Infectious Diseases
Pancreatitis Pathology and Treatment
article

A rare case of macroamylasemia in a patient with SARS-CoV-2 infection

Tilan Aponso, W. M. D. A. S. Wanninayake, N. M. M. Nawarathne
article en

Abstract

In this case report, we report about a 70-year-old hypertensive and asthmatic patient who was under inward treatment for mild COVID-19. He complained ofburning epigastric pain for one day and his elevated serum amylase level persisted months after the initial presentation. He underwent extensive investigations to exclude acute pancreatitis and other causes of high amylase levels. His amylase creatinine clearance ratio was 0.2%, his pre- polyethylene glycol(PEG) amylase concentration was 644 U/L, and his post-PEG amylase concentration was 10 U/L with a very low post-PEG recovery (1.55%). He was diagnosed with macroamylasemia.

BMC Infectious DiseasesVol. 25(1)
National Hospital of Sri Lanka (LK)
Openalex Percentile: Top 94%
Pancreatitis Pathology and Treatment
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