Phosphatidylserine as a tumor target for CAR-T cell therapy

PS holds promise as a target antigen for CAR-T cell therapy, underscoring the need to address fratricide as a key challenge in the development of PS-targeting CAR-T cells.

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Publication Details

Journal
Journal for ImmunoTherapy of Cancer
Published
2025-02-01
DOI
https://doi.org/10.1136/jitc-2024-009468
Citations
6
Primary Topic
CAR-T cell therapy research
Type
article
Field-Weighted Citation Impact
6.27

Funders

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article

Phosphatidylserine as a tumor target for CAR-T cell therapy

Sandra Hervás‐Stubbs, Iván Peñuelas, Marta Larráyoz, Felipe Prósper et al.
6 citations
Journal for ImmunoTherapy of Cancer
CAR-T cell therapy research
6.27
article

Phosphatidylserine as a tumor target for CAR-T cell therapy

Sandra Hervás‐Stubbs, Iván Peñuelas, Marta Larráyoz, Felipe Prósper, Flor Navarro, Isabel Vivas, María Collantes, Marta Gorraiz, Mercedes Iñarrairaegui, Carla Castro, Teresa Lozano, Pedro Justicia-Lirio, Félix Pareja, Noëlia Casares, Noa B. Martín‐Cófreces, Inés Sánchez-Moreno, Juan José Lasarte, Juan Roberto Rodriguez, Bruno Sangro, Celia Martín-Otal, Álvaro Gómez‐Morón
article en
6 citations

Abstract

PS holds promise as a target antigen for CAR-T cell therapy, underscoring the need to address fratricide as a key challenge in the development of PS-targeting CAR-T cells.

Journal for ImmunoTherapy of CancerVol. 13(2)
Universidad Complutense de Madrid (ES), Centro de Investigación en Red en Enfermedades Cardiovasculares (ES), Navarre Institute of Health Research (ES), Clinica Universidad de Navarra (ES), Universidad de Navarra (ES)
European Federation of Pharmaceutical Industries and Associations, Ministerio de Ciencia, Innovación y Universidades, Cancer Research UK, European Commission, Ministerio de Ciencia e Innovación, Associazione Italiana per la Ricerca sul Cancro, Centro de Investigación Biomédica en Red Enfermedades Cardiovasculares, Centro de Investigación Biomédica en Red de Cáncer, Departamento de Salud, Gobierno de Navarra, Gobierno de Navarra, Dirección General de Industria, Energia y Proyectos Estrategicos S3, Gobierno de Navarra, Instituto de Salud Carlos III, European Regional Development Fund, Agencia Estatal de Investigación
Good health and well-being
Openalex Percentile: Top 4%
CAR-T cell therapy research
6.27
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