ZHX2 inhibits diabetes-induced liver injury and ferroptosis by epigenetic silence of YTHDF2

These findings highlight the involvement of the ZHX2-YTHDF2-ferroptosis pathway in DM-induced liver injury and suggest that targeting this pathway may hold therapeutic potential for improving such injuries.

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Publication Details

Journal
Nutrition and Diabetes
Published
2025-02-22
DOI
https://doi.org/10.1038/s41387-025-00355-0
Citations
9
Primary Topic
Epigenetics and DNA Methylation
Type
article
Field-Weighted Citation Impact
7.25
Controls
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article

ZHX2 inhibits diabetes-induced liver injury and ferroptosis by epigenetic silence of YTHDF2

Wei Meng, Linghua Li
9 citations
Nutrition and Diabetes
Epigenetics and DNA Methylation
7.25
article

ZHX2 inhibits diabetes-induced liver injury and ferroptosis by epigenetic silence of YTHDF2

Wei Meng, Linghua Li
article en
9 citations

Abstract

These findings highlight the involvement of the ZHX2-YTHDF2-ferroptosis pathway in DM-induced liver injury and suggest that targeting this pathway may hold therapeutic potential for improving such injuries.

Nutrition and DiabetesVol. 15(1)
Southwest Medical University (CN), Affiliated Hospital of Southwest Medical University (CN)
Good health and well-being
Openalex Percentile: Top 3%
Epigenetics and DNA Methylation
7.25
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ZHX2 inhibits diabetes-induced liver injury and ferroptosis by epigenetic silence of YTHDF2 — Wei Meng, Linghua Li · Nutrition and Diabetes (2025) | TGRS Research Map | TGRS