Neurocysticercosis: A Case of an Unusual Cause of Seizures

Neurocysticercosis is a parasitic infestation of the central nervous system caused by larva of the helminth <i>Taenia solium</i>. It is a relatively uncommon aetiology for seizures with varying presentations which are dependent on the stage of the cyst, its location and the immune response of the host. Incidence is rising in developing countries due to renewed interest in piggery. Associated risk factors include poor sanitary condition, rearing pigs or consumption of pork meat and overcrowded living conditions. Diagnostic yield has improved in recent years following relative improved health care seeking attitude, availability of neuroimaging modalities such as cranial magnetic resonance imaging and pathologic analysis of resected tissue specimen. Though prevalence has been domiciled in rural and suburban communities, an increase in global transmigration of individuals has led to some incidence in developed counties. The advent of cysticidal therapy which is complementary to surgical resection of symptomatic lesions has helped improve the prognosis and attenuate disease progression in these patients while improving clinical outcomes of treatment. We present a 23-year-old male patient with adult onset seizures who had neuroimaging and brain biopsy with histopathologic diagnosis of neurocysticercosis. The disease should be entertained in a patient with adult onset seizure residing in a potentially endemic area. We also encourage multidisciplinary management for optimal outcome.

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Journal
Journal of Surgery
Published
2025-02-20
DOI
https://doi.org/10.11648/j.js.20251301.15
Primary Topic
Parasitic infections in humans and animals
Type
article
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article

Neurocysticercosis: A Case of an Unusual Cause of Seizures

EO Komolafe, Kelechi Michael Azode, B J Olasode
Journal of Surgery
Parasitic infections in humans and animals
article

Neurocysticercosis: A Case of an Unusual Cause of Seizures

EO Komolafe, Kelechi Michael Azode, B J Olasode
article en

Abstract

Neurocysticercosis is a parasitic infestation of the central nervous system caused by larva of the helminth <i>Taenia solium</i>. It is a relatively uncommon aetiology for seizures with varying presentations which are dependent on the stage of the cyst, its location and the immune response of the host. Incidence is rising in developing countries due to renewed interest in piggery. Associated risk factors include poor sanitary condition, rearing pigs or consumption of pork meat and overcrowded living conditions. Diagnostic yield has improved in recent years following relative improved health care seeking attitude, availability of neuroimaging modalities such as cranial magnetic resonance imaging and pathologic analysis of resected tissue specimen. Though prevalence has been domiciled in rural and suburban communities, an increase in global transmigration of individuals has led to some incidence in developed counties. The advent of cysticidal therapy which is complementary to surgical resection of symptomatic lesions has helped improve the prognosis and attenuate disease progression in these patients while improving clinical outcomes of treatment. We present a 23-year-old male patient with adult onset seizures who had neuroimaging and brain biopsy with histopathologic diagnosis of neurocysticercosis. The disease should be entertained in a patient with adult onset seizure residing in a potentially endemic area. We also encourage multidisciplinary management for optimal outcome.

Journal of SurgeryVol. 13(1)
Obafemi Awolowo University Teaching Hospitals Complex (NG)
Openalex Percentile: Top 96%
Parasitic infections in humans and animals
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Neurocysticercosis: A Case of an Unusual Cause of Seizures — EO Komolafe, Kelechi Michael Azode, et al. · Journal of Surgery (2025) | TGRS Research Map | TGRS