Carcinomatous Degeneration of Crohn's Disease About a Case at G-Point CHU / Mali

Aim: The aim of this study is to report the computed tomography characteristics of the degeneration of Crohn's disease. Patient: We report the observation of an 18-year-old girl admitted to the internal medicine department of the CHU Point G for diffuse abdominal pain predominantly in the right iliac fossa with diarrhea that has progressed since childhood but poorly followed. In whom the abdominal CT scan and abdominopelvic ultrasound performed revealed irregular vascular thickening of the wall of the terminal ileum and the cecum. At the end of these examinations, the diagnostic hypothesis of atypical Crohn's disease was adopted. Histology of the transverse colon specimen showed fragments of mucosa with an edematous chorion and an inflammatory infiltrate of omental and gigantocellular granuloma. On the other hand, that of the part of the ileocecal region showed a persistence of mucosecretion and the presence of columnar cells with an oval nucleus not exceeding 3/4 of the height of the epithelium and a little marked polymorphism in connection with neoplasia. certain low grade intraepithelial colic. This examination confirmed the diagnosis of carcinomatous degeneration of ileo-caeco-colic Crohn's disease. The clinical course at 6 months was favorable. However, the irregular thickening of the wall of the terminal ileum and the cecum is similar to the CT scan. Conclusion: Degeneration of Crohn's disease is rare. Imaging is involved in all phases of Crohn's disease. She makes the initial diagnosis, she specifies the topographical assessment of the lesions, she guides the treatment, she draws up the extension assessment during an evolutionary outbreak and degeneration.