Insulin Autoimmune Syndrome: A Chinese Expert Consensus Statement

Insulin autoimmune syndrome (IAS) is a rare autoimmune disorder characterized by spontaneous hypoglycemia. The incidence of IAS is higher in East Asian populations compared to other populations. Delayed diagnosis and treatment can lead to recurrent hypoglycemia, significant glucose fluctuations, and adverse clinical outcomes, including life-threatening situations. Currently, no standardized guidelines exist for the diagnosis and treatment of IAS. This consensus aims to provide a systematic summary of the epidemiology, triggers, pathogenesis, clinical manifestations, diagnosis, differential diagnosis, treatment, and prognosis of IAS, with the objective of standardizing its clinical management.

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Publication Details

Journal
Aging Medicine
Published
2025-02-01
DOI
https://doi.org/10.1002/agm2.70007
Citations
6
Primary Topic
Diabetes and associated disorders
Type
article
Field-Weighted Citation Impact
10.90

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article

Insulin Autoimmune Syndrome: A Chinese Expert Consensus Statement

Ming Xia Yuan, Qi Pan, Huabing Zhang
6 citations
Aging Medicine
Diabetes and associated disorders
10.90
article

Insulin Autoimmune Syndrome: A Chinese Expert Consensus Statement

Ming Xia Yuan, Qi Pan, Huabing Zhang
article en
6 citations

Abstract

Insulin autoimmune syndrome (IAS) is a rare autoimmune disorder characterized by spontaneous hypoglycemia. The incidence of IAS is higher in East Asian populations compared to other populations. Delayed diagnosis and treatment can lead to recurrent hypoglycemia, significant glucose fluctuations, and adverse clinical outcomes, including life-threatening situations. Currently, no standardized guidelines exist for the diagnosis and treatment of IAS. This consensus aims to provide a systematic summary of the epidemiology, triggers, pathogenesis, clinical manifestations, diagnosis, differential diagnosis, treatment, and prognosis of IAS, with the objective of standardizing its clinical management.

Aging MedicineVol. 8(1)
Capital Medical University (CN), Chinese Academy of Medical Sciences & Peking Union Medical College (CN), Peking Union Medical College Hospital (CN), Beijing Friendship Hospital (CN)
Shandong University, Harbin Medical University, Qilu Hospital of Shandong University, Sir Run Run Shaw Hospital, Inner Mongolia Medical University, Sun Yat-sen University, Capital Medical University, Central South University, Fudan University, Huazhong University of Science and Technology, Tongji University, Shihezi University, Zhejiang University, Chinese Academy of Medical Sciences, Wuhan University, Nanjing Medical University, Soochow University, Peking University, Southeast University, Peking Union Medical College Hospital, Peking University Third Hospital, General Hospital of People’s Liberation Army, Southern Medical University, Tianjin Medical University, Huashan Hospital, Peking Union Medical College, Guangxi Medical University, Dalian Medical University, Peking University People's Hospital, Shandong First Medical University, Guangdong Provincial People's Hospital, China-Japan Friendship Hospital, Tongji Medical College, Huazhong University of Science and Technology, Beijing Friendship Hospital, Capital Medical University
Good health and well-being
Openalex Percentile: Top 2%
Diabetes and associated disorders
10.90
DOIOpen Access PDFOpenAlex
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