Gorham stout disease in pregnancy

Gorham-Stout disease (GSD) is a rare disorder characterized by spontaneous and progressive bone resorption. Its clinical presentation varies from unremarkable to life-threatening, making diagnosis and treatment challenging. Despite extensive research, no definitive correlations have been established between GSD and age, gender, race, or environmental and infectious risk factors. A 32-year-old woman with GSD presented during her second pregnancy, experiencing gingival mass recurrence after 20 years. Biopsy revealed pyogenic granuloma, leading to 20 cycles of radiotherapy with no disease progression. She underwent an elective cesarean section at 37 weeks for low-lying placenta, recovering well postpartum. The limited documentation of GSD in pregnant women complicates diagnosis and management. Outcomes vary widely, from life-threatening complications like chylothorax to unremarkable cases. Comprehensive understanding is crucial for providing appropriate prenatal, antenatal, and postnatal care for affected women in the future.