In Silico Analysis of Saroglitazar and Ferulic Acid Binding to Human Ketohexokinase: Implications for Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD)
The study shows that saroglitazar and ferulic acid are potent KHK inhibitors for metabolic diseases, including MASLD, suggesting multi-target treatments.
Authors
- Gyan Vardhan (ORCID: https://orcid.org/0000-0002-7689-1482)
- Puneet Dhamija (ORCID: https://orcid.org/0000-0002-2890-4939)
- Amol Dehade
- Vinay Kumar (ORCID: https://orcid.org/0000-0002-0627-2301)
- Anurag Tiwari (ORCID: https://orcid.org/0000-0002-4772-6672)
- Kalpana Tiwari
- Brijesh Kumar
Institutions
- All India Institute of Medical Sciences Rishikesh (IN)
- Banaras Hindu University (IN)
Publication Details
- Journal
- Cureus
- Published
- 2025-02-22
- DOI
- https://doi.org/10.7759/cureus.79437
- Citations
- 2
- Primary Topic
- Liver Disease Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 2.71