Comparative RNA-Seq analysis of differentially expressed genes in the sertoli cells of yak and cattle-yak
Compared with yak Sertoli cells, the expression of genes related to protein activation, cell function, and membranous organelle composition in cattle-yak Sertoli cells appeared to be abnormal. The potential defects in cattle-yak Sertoli cells may hinder the creation of a suitable environment for spermatogenesis, which could be one of the factors contributing to male cattle-yak sterility. Claudin-11 might be a potentially important gene for further research into cattle-yak male sterility.
Authors
- Jincheng Zhong (ORCID: https://orcid.org/0000-0002-1734-5887)
- Xin Cai (ORCID: https://orcid.org/0000-0002-7191-2571)
- Binglin Yue (ORCID: https://orcid.org/0000-0002-2505-4975)
- Zhijuan Wu (ORCID: https://orcid.org/0000-0001-5878-108X)
- Mingxiu Wang (ORCID: https://orcid.org/0009-0008-2150-9929)
- Kemin Jing
- Zhixin Chai (ORCID: https://orcid.org/0000-0002-8671-6178)
- Peng Zhang (ORCID: https://orcid.org/0000-0002-7779-8474)
- Xinrui Liu (ORCID: https://orcid.org/0000-0003-2348-5891)
- Xuemei Chen (ORCID: https://orcid.org/0000-0003-1909-8530)
Institutions
- Sichuan University (CN)
- Southwest Minzu University (CN)
Publication Details
- Journal
- BMC Veterinary Research
- Published
- 2025-02-22
- DOI
- https://doi.org/10.1186/s12917-025-04540-2
- Primary Topic
- Animal Genetics and Reproduction
- Type
- article
- Field-Weighted Citation Impact
- 0.00