Early Prediction of Radiation Pneumonitis in Patients With Lung Cancer Treated With Immunotherapy Through Monitoring of Plasma Chemokines
In this prospective study, plasma chemokines predict future risk of symptomatic RP in patients with lung cancer who have received prior immunotherapy. Despite with moderate AUC, the scoring system based on plasma chemokines and mean lung dose is a feasible tool for predicting symptomatic RP, aiding in tailoring personalized and optimal treatment for patients.
Authors
- Zhijie Fan (ORCID: https://orcid.org/0000-0002-8748-0224)
- Guang Han (ORCID: https://orcid.org/0000-0001-5500-3338)
- Lihua Fan (ORCID: https://orcid.org/0000-0001-8308-5713)
- Lingyan Xiao (ORCID: https://orcid.org/0000-0001-7455-9868)
- Yulong Yu (ORCID: https://orcid.org/0000-0003-0170-087X)
- Qian Li (ORCID: https://orcid.org/0000-0003-0359-5604)
- Sheng Wang (ORCID: https://orcid.org/0000-0002-4797-5310)
- Ying Li (ORCID: https://orcid.org/0000-0003-2314-9599)
- Bo Liu (ORCID: https://orcid.org/0000-0001-5118-1890)
- Duo Xu (ORCID: https://orcid.org/0000-0001-7880-9123)
- Li Ma (ORCID: https://orcid.org/0000-0003-4347-9560)
- Xi Wang (ORCID: https://orcid.org/0000-0002-1285-7795)
- Xianglin Yuan
Institutions
- Ezhou Central Hospital (CN)
- Tongji Hospital (CN)
- Hubei Cancer Hospital (CN)
- First People's Hospital of Jingzhou (CN)
- Huazhong University of Science and Technology (CN)
Publication Details
- Journal
- International Journal of Radiation Oncology*Biology*Physics
- Published
- 2025-02-22
- DOI
- https://doi.org/10.1016/j.ijrobp.2025.02.011
- Citations
- 7
- Primary Topic
- Lung Cancer Research Studies
- Type
- article
- Field-Weighted Citation Impact
- 7.32
Funders
- National Natural Science Foundation of China