Case report: Typhoid fever due to laboratory acquired Salmonella paratyphi confirmed through antibiotic sensitivity testing

Enteric fever is a major public health concern in developing countries. Enteric fever can result from Salmonella typhi and Salmonella paratyphi infections after consuming contaminated food or water. The increase in widespread drug resistance is severely limiting treatment options for this serious disease. This case report covers a 23 year old patient history who got lab acquired infection of Salmonella paratyphi A infection. Initially, he experienced symptoms of fever, and irritability, which progressed to severe loose motions and high-grade fever. Due to the worsening condition, the patient was admitted to the hospital where blood testing was done and the patient was advised to be treated with Azithromycin. With appropriate treatment, the patient showed significant improvement, including resolution of fever and normal bowl movement. Management of Salmonella is often challenging but prompt administration of appropriate antibiotics based on sensitivity testing is crucial for successful management. This case emphasizes the importance of early recognition and effective management of this uncommon yet severe complication of Salmonella infection.

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Publication Details

Journal
Journal of Cellular and Molecular Immunology
Published
2025-02-22
DOI
https://doi.org/10.46439/immunol.3.028
Primary Topic
Salmonella and Campylobacter epidemiology
Type
article
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article

Case report: Typhoid fever due to laboratory acquired Salmonella paratyphi confirmed through antibiotic sensitivity testing

Kaleem Ullah, Fareeha Sohail, Shehreen Sohail
Journal of Cellular and Molecular Immunology
Salmonella and Campylobacter epidemiology
article

Case report: Typhoid fever due to laboratory acquired Salmonella paratyphi confirmed through antibiotic sensitivity testing

Kaleem Ullah, Fareeha Sohail, Shehreen Sohail
article en

Abstract

Enteric fever is a major public health concern in developing countries. Enteric fever can result from Salmonella typhi and Salmonella paratyphi infections after consuming contaminated food or water. The increase in widespread drug resistance is severely limiting treatment options for this serious disease. This case report covers a 23 year old patient history who got lab acquired infection of Salmonella paratyphi A infection. Initially, he experienced symptoms of fever, and irritability, which progressed to severe loose motions and high-grade fever. Due to the worsening condition, the patient was admitted to the hospital where blood testing was done and the patient was advised to be treated with Azithromycin. With appropriate treatment, the patient showed significant improvement, including resolution of fever and normal bowl movement. Management of Salmonella is often challenging but prompt administration of appropriate antibiotics based on sensitivity testing is crucial for successful management. This case emphasizes the importance of early recognition and effective management of this uncommon yet severe complication of Salmonella infection.

Journal of Cellular and Molecular ImmunologyVol. 3(1)
University of Central Punjab (PK), Government College University, Lahore (PK)
Openalex Percentile: Top 97%
Salmonella and Campylobacter epidemiology
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Case report: Typhoid fever due to laboratory acquired Salmonella paratyphi confirmed through antibiotic sensitivity testing — Kaleem Ullah, Fareeha Sohail, et al. · Journal of Cellular and Molecular Immunology (2025) | TGRS Research Map | TGRS