Formononetin Alleviates the Inflammatory Response Induced by Carotid Balloon Injury in Rats via the PP2A/MAPK Axis

FOR can effectively reduce vascular damage and inflammation after coronary artery bypass grafting through the PP2A/MAPK axis, enhance vascular remodeling, and restore protein expression profiles. These findings suggest FOR as a promising therapeutic agent for vascular injuries.

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Publication Details

Journal
Immunological Investigations
Published
2025-02-22
DOI
https://doi.org/10.1080/08820139.2025.2470323
Citations
2
Primary Topic
S100 Proteins and Annexins
Type
article
Field-Weighted Citation Impact
1.61
Controls
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article

Formononetin Alleviates the Inflammatory Response Induced by Carotid Balloon Injury in Rats via the PP2A/MAPK Axis

Lili Jiang, Shumeng Yang, Yubin Li, Xuejun Wu et al.
2 citations
Immunological Investigations
S100 Proteins and Annexins
1.61
article

Formononetin Alleviates the Inflammatory Response Induced by Carotid Balloon Injury in Rats via the PP2A/MAPK Axis

Lili Jiang, Shumeng Yang, Yubin Li, Xuejun Wu, Huanli Zhao, Huiying Yu
article en
2 citations

Abstract

FOR can effectively reduce vascular damage and inflammation after coronary artery bypass grafting through the PP2A/MAPK axis, enhance vascular remodeling, and restore protein expression profiles. These findings suggest FOR as a promising therapeutic agent for vascular injuries.

Immunological InvestigationsVol. 54(5)
Linyi People's Hospital (CN), Shandong Provincial Hospital (CN), Shandong First Medical University (CN)
Good health and well-being
Openalex Percentile: Top 19%
S100 Proteins and Annexins
1.61
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