Genetically predicted circulating immune cells and cytokines reveal the causal role of immune factors on female infertility: a two-sample mendelian randomization study
Our results highlight that immune response contributes to female infertility risk through subtype-specific mechanisms, providing clues for following clinical research and treatment.
Authors
- Kaixuan Dong
- Lan Zhu
- Jing Yan (ORCID: https://orcid.org/0000-0002-0307-1635)
- Hongjia Zhu (ORCID: https://orcid.org/0000-0003-4643-8801)
- Zhaoliang Dou
- Hui-xi Chen
- He-Feng Huang
- Naixin Xu
- Yi Cheng (ORCID: https://orcid.org/0009-0004-2128-6834)
- Jinyou Mo
Institutions
- Shanghai Jiao Tong University (CN)
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Peking Union Medical College Hospital (CN)
- International Peace Maternity & Child Health Hospital (CN)
- Obstetrics and Gynecology Hospital of Fudan University (CN)
- First Affiliated Hospital Zhejiang University (CN)
Publication Details
- Journal
- BMC Pregnancy and Childbirth
- Published
- 2025-02-22
- DOI
- https://doi.org/10.1186/s12884-025-07318-4
- Citations
- 2
- Primary Topic
- Reproductive System and Pregnancy
- Type
- article
- Field-Weighted Citation Impact
- 1.59