Effect of 0.8mg/ml Losartan on Corneal Opacities

Losartan, commonly used as an angiotensin receptor II inhibitor for hypertension, has recently revealed additional therapeutic properties. Studies demonstrate its potential in treating liver fibrosis, mitigating heart disease secondary to radiation, reducing skin scar formation, and even reversing renal cortical fibrosis. In a specific case, a female patient suffering from persistent bilateral nummular keratitis and corneal opacities experienced significant improvement in her left eye after using 0.8mg/ml Losartan eye drops. Untreated right eye showed no change. Based on the positive outcome, patient was offered same treatment in her right eye as well with monthly follow-ups, which she happily accepted. The stark contrast between the treated and untreated eye highlights the promising role of Losartan in treating corneal opacities.

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Publication Details

Journal
Pakistan Journal of Medical Sciences
Published
2025-02-22
DOI
https://doi.org/10.12669/pjms.41.3.11237
Citations
3
Primary Topic
Glaucoma and retinal disorders
Type
article
Field-Weighted Citation Impact
5.12
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article

Effect of 0.8mg/ml Losartan on Corneal Opacities

Aisha Fawad, Waqar Muzaffar, Unnab Anjum, Mahad Naseer Amer
3 citations
Pakistan Journal of Medical Sciences
Glaucoma and retinal disorders
5.12
article

Effect of 0.8mg/ml Losartan on Corneal Opacities

Aisha Fawad, Waqar Muzaffar, Unnab Anjum, Mahad Naseer Amer
article en
3 citations

Abstract

Losartan, commonly used as an angiotensin receptor II inhibitor for hypertension, has recently revealed additional therapeutic properties. Studies demonstrate its potential in treating liver fibrosis, mitigating heart disease secondary to radiation, reducing skin scar formation, and even reversing renal cortical fibrosis. In a specific case, a female patient suffering from persistent bilateral nummular keratitis and corneal opacities experienced significant improvement in her left eye after using 0.8mg/ml Losartan eye drops. Untreated right eye showed no change. Based on the positive outcome, patient was offered same treatment in her right eye as well with monthly follow-ups, which she happily accepted. The stark contrast between the treated and untreated eye highlights the promising role of Losartan in treating corneal opacities.

Pakistan Journal of Medical SciencesVol. 41(3)
National University of Medical Sciences (PK), Army Medical College (PK)
Good health and well-being
Openalex Percentile: Top 6%
Glaucoma and retinal disorders
5.12
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