Bladder drugs and risk of dementia: Danish nationwide active comparator study

In this study, all types of anticholinergic bladder drugs were associated with an increased risk of dementia compared with non-use, but not when applying the active comparator of the β3 agonist bladder drug mirabegron. These findings highlight the relevance of using an active comparator. Future research should evaluate the risk of cognitive impairment and dementia for both types of bladder drugs.

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Institutions

Publication Details

Journal
BMJ Medicine
Published
2025-02-01
DOI
https://doi.org/10.1136/bmjmed-2024-001125
Citations
1
Primary Topic
Urinary Bladder and Prostate Research
Type
article
Field-Weighted Citation Impact
1.84

Funders

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article

Bladder drugs and risk of dementia: Danish nationwide active comparator study

Gunhild Waldemar, Amani Meaidi, Thomas Munk Laursen, Nelsan Pourhadi et al.
1 citations
BMJ Medicine
Urinary Bladder and Prostate Research
1.84
article

Bladder drugs and risk of dementia: Danish nationwide active comparator study

Gunhild Waldemar, Amani Meaidi, Thomas Munk Laursen, Nelsan Pourhadi, Christina Jensen‐Dahm, Janet Janbek, Christiane Gasse
article en
1 citations

Abstract

In this study, all types of anticholinergic bladder drugs were associated with an increased risk of dementia compared with non-use, but not when applying the active comparator of the β3 agonist bladder drug mirabegron. These findings highlight the relevance of using an active comparator. Future research should evaluate the risk of cognitive impairment and dementia for both types of bladder drugs.

BMJ MedicineVol. 4(1)
University of Copenhagen (DK), Aarhus University (DK), Aarhus University Hospital (DK), Copenhagen University Hospital (DK), Rigshospitalet (DK), Danish Cancer Society (DK)
Gentofte Hospital, Rigshospitalet, Ministeriet Sundhed Forebyggelse
Good health and well-being
Openalex Percentile: Top 20%
Urinary Bladder and Prostate Research
1.84
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Bladder drugs and risk of dementia: Danish nationwide active comparator study — Gunhild Waldemar, Amani Meaidi, et al. · BMJ Medicine (2025) | TGRS Research Map | TGRS