Association between dose to cardiac structures and overall survival: A multivariable analysis in a large, multi-institutional database of stage III NSCLC patients with external validation
Although significant associations between cardiovascular parameters and survival were found, their small effect sizes should be considered when prioritizing cardiac sparing in stage III NSCLC treatment.
Authors
- Nanna M. Sijtsema
- Andrew Hope (ORCID: https://orcid.org/0000-0001-6793-2863)
- Robin Wijsman (ORCID: https://orcid.org/0000-0001-5139-0908)
- Richard Canters (ORCID: https://orcid.org/0000-0002-0606-9805)
- Zeno A.R. Gouw (ORCID: https://orcid.org/0000-0001-6206-6839)
- Johan Bussink (ORCID: https://orcid.org/0000-0002-5751-4796)
- Barbara Stam
- Albrecht Weiß (ORCID: https://orcid.org/0009-0003-1112-7277)
- Miguel Garrett Fernandes
- Jan‐Jakob Sonke (ORCID: https://orcid.org/0000-0001-5155-5274)
- Esther G.C. Troost (ORCID: https://orcid.org/0000-0001-9550-9050)
- Dirk De Ruysscher (ORCID: https://orcid.org/0000-0002-1214-3557)
- R. Monshouwer
Institutions
- University Health Network (CA)
- University Medical Center Groningen (NL)
- Radboud University Nijmegen (NL)
- University of Groningen (NL)
- Heidelberg University (DE)
- Helmholtz-Zentrum Dresden-Rossendorf (DE)
- University Hospital Heidelberg (DE)
- Princess Margaret Cancer Centre (CA)
- Radboud University Medical Center (NL)
- The Netherlands Cancer Institute (NL)
- Maastricht University (NL)
- Radboud Institute for Molecular Life Sciences (NL)
- Maastro Clinic (NL)
Publication Details
- Journal
- Radiotherapy and Oncology
- Published
- 2025-02-22
- DOI
- https://doi.org/10.1016/j.radonc.2025.110821
- Primary Topic
- Lung Cancer Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00