Are Causal Statements Reported in Pharmacovigilance Disproportionality Analyses Using Individual Case Safety Reports Exaggerated in Related Citations? A Meta-epidemiological Study
Nearly half of the studies citing pharmacovigilance disproportionality analyses results used causal claims, particularly when the causal language used in the source article was stronger. There is a need for higher caution when writing, interpreting, and citing disproportionality studies.
Authors
- Matthieu Roustit (ORCID: https://orcid.org/0000-0003-4475-1626)
- Charles Khouri (ORCID: https://orcid.org/0000-0002-8427-8573)
- Bruno Revol (ORCID: https://orcid.org/0000-0003-2931-2940)
- Francesco Salvo (ORCID: https://orcid.org/0000-0003-3210-7171)
- Michele Fusaroli (ORCID: https://orcid.org/0000-0002-0254-2212)
- Emanuel Raschi (ORCID: https://orcid.org/0000-0003-0487-7996)
- Claire Bernardeau (ORCID: https://orcid.org/0000-0002-3828-4833)
- Jean‐Luc Cracowski (ORCID: https://orcid.org/0000-0003-0787-1469)
Institutions
- Université de Bordeaux (FR)
- Inserm (FR)
- Centre Hospitalier Universitaire de Grenoble (FR)
- Centre Hospitalier Universitaire de Bordeaux (FR)
- Bordeaux Population Health (FR)
- Université Grenoble Alpes (FR)
- University of Bologna (IT)
Publication Details
- Journal
- Drug Safety
- Published
- 2025-02-22
- DOI
- https://doi.org/10.1007/s40264-025-01524-x
- Citations
- 4
- Primary Topic
- Pharmacovigilance and Adverse Drug Reactions
- Type
- article
- Field-Weighted Citation Impact
- 5.23