The 2-Step Mendelian Randomisation Study Assesses Genetic Causality and Potential Mediators of Periodontal Disease and Atrial Fibrillation
Our findings demonstrated the genetic causality between periodontal disease and AF. Maintaining oral hygiene, adopting standardised periodontal therapy, and restricting body weight are critical goals for patients with periodontal disease to mitigate disease progression to AF.
Authors
- Lian-Xin Wang (ORCID: https://orcid.org/0000-0001-7321-4315)
- Yuanhui Hu (ORCID: https://orcid.org/0009-0006-6669-5708)
- Zezhen Guo
- Jiaran Li (ORCID: https://orcid.org/0009-0002-9910-1591)
- Huan Wang (ORCID: https://orcid.org/0000-0002-7010-3086)
- Xiaohan Zhang (ORCID: https://orcid.org/0000-0001-9618-8973)
- Chengzhong Lian
- Bai Du (ORCID: https://orcid.org/0009-0007-4812-1222)
- Naixu Liu
- Shuqing Shi
Institutions
- Nanjing University of Chinese Medicine (CN)
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Guang’anmen Hospital (CN)
- Macquarie University (AU)
Publication Details
- Journal
- International Dental Journal
- Published
- 2025-02-22
- DOI
- https://doi.org/10.1016/j.identj.2024.12.029
- Citations
- 6
- Primary Topic
- Genetic Associations and Epidemiology
- Type
- article
- Field-Weighted Citation Impact
- 10.90
Funders
- China Academy of Chinese Medical Sciences