Treatment of Primary Pulmonary Synovial Sarcoma in a Low-Resource Country: A Case Report

Primary synovial sarcoma of the lung is a rare malignant cancer. The symptoms are nonspecific; they may not appear at all, so it is often diagnosed in the late stages. Moreover, accurate diagnosis requires a combination of the results of clinical evaluation, imaging, and histological examinations, since the results of these methods separately are not very specific and may lead to misdiagnosis. Given the rarity of this diagnosis, the therapy is not standardized. The preferred treatment regimen involves surgery combined with neoadjuvant or adjuvant radio- and chemotherapy. This case report describes a 67-year-old male patient who was diagnosed with pulmonary synovial sarcoma. Diagnosis was confirmed via computed tomography (CT) imaging and immunohistochemical (IHC) examination. After surgical removal, the patient underwent adjuvant radiotherapy.

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Journal
Cureus
Published
2025-02-22
DOI
https://doi.org/10.7759/cureus.79463
Primary Topic
Sarcoma Diagnosis and Treatment
Type
article
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article

Treatment of Primary Pulmonary Synovial Sarcoma in a Low-Resource Country: A Case Report

Sergo Mkhitaryan, Narek Shaverdian, A. V. Gasparyan, Tatul Saghatelyan et al.
Cureus
Sarcoma Diagnosis and Treatment
article

Treatment of Primary Pulmonary Synovial Sarcoma in a Low-Resource Country: A Case Report

Sergo Mkhitaryan, Narek Shaverdian, A. V. Gasparyan, Tatul Saghatelyan, Ս. Հ. Աբրահամյան
article en

Abstract

Primary synovial sarcoma of the lung is a rare malignant cancer. The symptoms are nonspecific; they may not appear at all, so it is often diagnosed in the late stages. Moreover, accurate diagnosis requires a combination of the results of clinical evaluation, imaging, and histological examinations, since the results of these methods separately are not very specific and may lead to misdiagnosis. Given the rarity of this diagnosis, the therapy is not standardized. The preferred treatment regimen involves surgery combined with neoadjuvant or adjuvant radio- and chemotherapy. This case report describes a 67-year-old male patient who was diagnosed with pulmonary synovial sarcoma. Diagnosis was confirmed via computed tomography (CT) imaging and immunohistochemical (IHC) examination. After surgical removal, the patient underwent adjuvant radiotherapy.

CureusVol. 17(2)
Memorial Sloan Kettering Cancer Center (US), National Statistical Service of the Republic of Armenia (AM), Yerevan State Medical University (AM)
Zero hunger
Openalex Percentile: Top 95%
Sarcoma Diagnosis and Treatment
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Treatment of Primary Pulmonary Synovial Sarcoma in a Low-Resource Country: A Case Report — Sergo Mkhitaryan, Narek Shaverdian, et al. · Cureus (2025) | TGRS Research Map | TGRS