Contrast-enhanced photon-counting detector CT for discriminating local recurrence from postoperative changes after resection of pancreatic ductal adenocarcinoma

Distinguishing recurrence from postoperative changes on CT after pancreatic ductal adenocarcinoma resection is challenging. PCD-CT spectral variable values differed significantly between local tumor recurrence (LTR) and postoperative changes (POC). Logistic regression of spectral variables can help distinguish LTR from POC. The late arterial phase-based model reached an AUC of 0.919 with 94% sensitivity and 84% specificity.