Is a single lethal electric field threshold sufficient to characterize the lesion size in computational modeling of cardiac pulsed-field ablation?
Our computational model shows that a single lethal electric field threshold is insufficient to accurately predict both lesion depth and width in cardiac PFA. Our study suggests that for the given PFA waveforms, a threshold between 270 and 500 V/cm provides satisfactory lesion depth estimations, and a higher threshold between 790 and 1000 V/cm better captures the lesion width.
Authors
- Zoraida Moreno Weidmann (ORCID: https://orcid.org/0000-0003-1071-4077)
- Antoni Ivorra (ORCID: https://orcid.org/0000-0001-7718-8767)
- María José Guerra Palmero (ORCID: https://orcid.org/0000-0001-5397-9177)
- David Viladés‐Medel (ORCID: https://orcid.org/0000-0002-3638-9703)
- Tomás García-Sánchez (ORCID: https://orcid.org/0000-0002-1115-0683)
- Gerard Amorós Figueras
- Argyrios Petras (ORCID: https://orcid.org/0000-0002-3278-620X)
- Luca Gerardo‐Giorda (ORCID: https://orcid.org/0000-0001-8467-1247)
Institutions
- Johannes Kepler University of Linz (AT)
- Universitat Autònoma de Barcelona (ES)
- Universitat Pompeu Fabra (ES)
- Hospital de Sant Pau (ES)
- Johann Radon Institute for Computational and Applied Mathematics (AT)
Publication Details
- Journal
- Heart Rhythm O2
- Published
- 2025-02-22
- DOI
- https://doi.org/10.1016/j.hroo.2025.02.014
- Citations
- 4
- Primary Topic
- Microbial Inactivation Methods
- Type
- article
- Field-Weighted Citation Impact
- 4.93
Funders
- Ministerio de Ciencia, Innovación y Universidades
- Austrian Science Fund
- Österreichische Forschungsförderungsgesellschaft
- Instituto de Salud Carlos III
- HORIZON EUROPE Marie Sklodowska-Curie Actions