Long-Term Sequelae of COVID-19: A Six-Month Follow-Up Study at a Tertiary Care Centre in South Kerala

Background: COVID-19, emerging in December 2019, has manifested as a significant global health concern. While its acute phase is extensively documented, the long-term effects post-recovery remain less understood, particularly in specific regions such as Kerala, India. This study investigates the prolonged complications encountered by COVID-19 survivors from a tertiary care centre in South Kerala.Objectives: This research aimed to determine the prevalence and clinical characteristics of post-COVID complications among survivors in South Kerala.Method: A prospective observational study was conducted from March 2021 to September 2022, involving 184 participants who recovered from COVID-19. All participants were over 18 years of age and had confirmed COVID-19 recovery. Data collection involved interviews and examinations using a validated questionnaire one month post- recovery, continuing monthly for six months. Data on medical history, symptoms, and clinical investigations were gathered, followed by statistical analysis using SPSS 2.0.Results: The cohort consisted of 184 participants, with an average age of 51.5 years and 52.2% male. Among them, 46.2% had mild COVID-19, 36.4% moderate, and 17.4% critical illness. Co-morbidities were prevalent: hypertension (35.9%), diabetes (35.3%), and coronary artery disease (10.9%).At one month post-recovery, 69% experienced post-COVID complications, with fatigue (43.5%) being most common. By six months, complications reduced to 22.8%, showcasing the importance of supportive care in recovery.Conclusion: This study underscores the necessity for continuous medical support and monitoring of COVID-19 survivors to manage long-term health challenges effectively. Identifying post-COVID symptoms enables healthcare providers to customise follow-up care, highlighting the need for evidence-based guidelines to address post-COVID syndrome. How to cite this article: George A M, Asokan A G, Kuriakose M E. Long- Term Sequelae of COVID-19: A Six-Month Follow-Up Study at a Tertiary Care Centre in South Kerala.J Commun Dis. 2024;56(4):62-69. DOI: https://doi.org/10.24321/0019.5138.202471