Recto Sigmoid Sub-Mucosal Bleeding Due to Warfarin over Anticoagulation Presenting as Intestinal Obstruction

Patients on anticoagulation therapy, particularly those on warfarin, are at risk of gastrointestinal bleeding, gum bleeding, hematuria, and ecchymosis. However, it is rare for such patients to present with intramural or submucosal bleeding leading to intestinal obstructive symptoms. Sub-mucosal intestinal bleeding due to prolonged anticoagulant use is uncommon. Literature suggests that the duodenum and small intestine are common locations for anticoagulant-induced hematomas, occurring in approximately 1 case per 2,500 anticoagulated patients per year. However, intramural colonic hematomas are rarely reported. Spontaneous anticoagulant induced hematomas may develop as early as 10 days after starting therapy. We report the case of a 63-year-old female who presented with recto-sigmoid sub-mucosal bleeding causing obstructive symptoms. The patient was managed surgically with laparotomy, resulting in significant improvement, and was scheduled for follow-up to evaluate the feasibility of reintroducing anticoagulation therapy.

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Publication Details

Journal
Ethiopian Journal of Health Sciences
Published
2025-02-06
DOI
https://doi.org/10.4314/ejhs.v35i1.9
Citations
2
Primary Topic
Case Reports on Hematomas
Type
article
Field-Weighted Citation Impact
4.01

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article

Recto Sigmoid Sub-Mucosal Bleeding Due to Warfarin over Anticoagulation Presenting as Intestinal Obstruction

Markos Tesfaye, Fithanegest Teferra Gebretekle, Tibebu Tesfaye
2 citations
Ethiopian Journal of Health Sciences
Case Reports on Hematomas
4.01
article

Recto Sigmoid Sub-Mucosal Bleeding Due to Warfarin over Anticoagulation Presenting as Intestinal Obstruction

Markos Tesfaye, Fithanegest Teferra Gebretekle, Tibebu Tesfaye
article en
2 citations

Abstract

Patients on anticoagulation therapy, particularly those on warfarin, are at risk of gastrointestinal bleeding, gum bleeding, hematuria, and ecchymosis. However, it is rare for such patients to present with intramural or submucosal bleeding leading to intestinal obstructive symptoms. Sub-mucosal intestinal bleeding due to prolonged anticoagulant use is uncommon. Literature suggests that the duodenum and small intestine are common locations for anticoagulant-induced hematomas, occurring in approximately 1 case per 2,500 anticoagulated patients per year. However, intramural colonic hematomas are rarely reported. Spontaneous anticoagulant induced hematomas may develop as early as 10 days after starting therapy. We report the case of a 63-year-old female who presented with recto-sigmoid sub-mucosal bleeding causing obstructive symptoms. The patient was managed surgically with laparotomy, resulting in significant improvement, and was scheduled for follow-up to evaluate the feasibility of reintroducing anticoagulation therapy.

Ethiopian Journal of Health SciencesVol. 35(1)
International Trachoma Initiative (ET), St. Paul's Hospital Millennium Medical College (ET)
Bill and Melinda Gates Foundation, World Health Organization
Openalex Percentile: Top 9%
Case Reports on Hematomas
4.01
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