Enhancing in-hospital mortality prediction in older patients with sepsis: the role of frailty indices and multidrug-resistance status in non-ICU wards—a proof-of-concept study
Incorporating frailty indices and MDR status of culture isolates into traditional prognostic parameters improves mortality prediction in older patients admitted with sepsis, enabling more accurate risk stratification and personalized treatment strategies.
Authors
- Paolo Mazzola (ORCID: https://orcid.org/0000-0002-0484-1136)
- Giuseppe Bellelli (ORCID: https://orcid.org/0000-0001-5430-0947)
- Andrea Piazzoli (ORCID: https://orcid.org/0009-0005-6843-5013)
- Andrea Ticinesi (ORCID: https://orcid.org/0000-0001-9171-8592)
- Chukwuma Okoye (ORCID: https://orcid.org/0000-0003-2969-7393)
- María Cristina Ferrara (ORCID: https://orcid.org/0000-0002-7971-5943)
- Alice Margherita Ornago (ORCID: https://orcid.org/0009-0008-7927-793X)
- Alberto Finazzi
- Elena Pinardi (ORCID: https://orcid.org/0009-0004-8068-9406)
- Beatrice Tonus
Institutions
- University of Parma (IT)
- Stockholm University (SE)
- Karolinska Institutet (SE)
- Azienda Ospedaliera San Gerardo (IT)
- Istituti di Ricovero e Cura a Carattere Scientifico (IT)
- University of Milano-Bicocca (IT)
Publication Details
- Journal
- Aging Clinical and Experimental Research
- Published
- 2025-02-22
- DOI
- https://doi.org/10.1007/s40520-025-02955-3
- Citations
- 1
- Primary Topic
- Frailty in Older Adults
- Type
- article
- Field-Weighted Citation Impact
- 1.22
Funders
- Università degli Studi di Milano
- Università degli Studi di Milano-Bicocca