Australia's rotavirus immunisation program: Impact on acute gastroenteritis and intussusception hospitalisations over 13 years
Over a 13-year period post-rotavirus vaccine introduction we document major sustained declines in hospitalisations coded as rotavirus and other AGE in age groups <20 years, with no change in intussusception hospitalisation rates in infants. Despite small increases in AGE hospitalisations in adults, likely due to increased PCR testing, our findings are consistent with highly favourable risk benefit ratio at whole-of-population level in Australia.
Authors
- Peter McIntyre (ORCID: https://orcid.org/0000-0001-5808-7450)
- Frank Beard (ORCID: https://orcid.org/0000-0002-9151-4781)
- Aditi Dey (ORCID: https://orcid.org/0000-0001-7178-8606)
- Stephen B. Lambert (ORCID: https://orcid.org/0000-0002-2709-193X)
- Kristine Macartney (ORCID: https://orcid.org/0000-0002-4675-0232)
- Joanne Jackson
- Han Wang (ORCID: https://orcid.org/0009-0007-8017-0083)
Institutions
- Children's Hospital at Westmead (AU)
- National Centre for Immunisation Research & Surveillance (AU)
Publication Details
- Journal
- Vaccine
- Published
- 2025-02-22
- DOI
- https://doi.org/10.1016/j.vaccine.2025.126789
- Primary Topic
- Viral gastroenteritis research and epidemiology
- Type
- article
- Field-Weighted Citation Impact
- 0.00