Synthesis, Characterization, and Anti-Mycobacterial Evaluation of Oxadiazole and Pyrazolone Derivatives

Hydrazides and hydrazones are important precursors for synthesizing heterocyclic compounds. This study focuses on the synthesis and characterization of pyrazolone and 1,3,4-oxadiazole derivatives using spectroscopic techniques. These compounds were screened for their anti-mycobacterial activity, showing promising results. Additionally, in silico ADMET predictions were performed to evaluate their chemical properties. The results indicate the potential of these derivatives as effective anti-tuberculosis agents, paving the way for further biological evaluations.