Development and Evaluation of Mouth Dissolving Anti - Inflammatory Tablet Containing Fenoprofen

The aim of this study was to formulate and evaluate a mouth - dissolving tablet of Fenoprofen, a nonsteroidal anti - inflammatory drug (NSAID), for rapid onset of action and improved patient compliance. Fenoprofen is known for its anti - inflammatory, analgesic, and antipyretic characteristics, but its conventional dosage forms have restrictions such as delayed onset of action and gastrointestinal irritation. In this work, we develop mouth - dissolving tablets using good excipients, add super disintegrants, make sure rapid disintegration and drug release. The tablets were analysed for various physicochemical variable such as disintegration time, drug content, in - vitro dissolution, and stability. The results shows that the improve formulation exhibited excellent disintegration and dissolution characteristics, with a significant upgrade in drug bioavailability correlate to standard formulations. The advanced mouth - dissolving tablets showed promise as a well - found alternative for delivering Fenoprofen in an efficient and patient - friendly manner.

Authors

Publication Details

Journal
International Journal of Science and Research (IJSR)
Published
2025-02-22
DOI
https://doi.org/10.21275/sr25217135130
Primary Topic
Pharmacological Effects of Natural Compounds
Type
article
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article

Development and Evaluation of Mouth Dissolving Anti - Inflammatory Tablet Containing Fenoprofen

Shefali S. Verma, Alka Verma
International Journal of Science and Research (IJSR)
Pharmacological Effects of Natural Compounds
article

Development and Evaluation of Mouth Dissolving Anti - Inflammatory Tablet Containing Fenoprofen

Shefali S. Verma, Alka Verma
article en

Abstract

The aim of this study was to formulate and evaluate a mouth - dissolving tablet of Fenoprofen, a nonsteroidal anti - inflammatory drug (NSAID), for rapid onset of action and improved patient compliance. Fenoprofen is known for its anti - inflammatory, analgesic, and antipyretic characteristics, but its conventional dosage forms have restrictions such as delayed onset of action and gastrointestinal irritation. In this work, we develop mouth - dissolving tablets using good excipients, add super disintegrants, make sure rapid disintegration and drug release. The tablets were analysed for various physicochemical variable such as disintegration time, drug content, in - vitro dissolution, and stability. The results shows that the improve formulation exhibited excellent disintegration and dissolution characteristics, with a significant upgrade in drug bioavailability correlate to standard formulations. The advanced mouth - dissolving tablets showed promise as a well - found alternative for delivering Fenoprofen in an efficient and patient - friendly manner.

International Journal of Science and Research (IJSR)Vol. 14(2)
Openalex Percentile: Top 96%
Pharmacological Effects of Natural Compounds
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