Development and Evaluation of Mouth Dissolving Anti - Inflammatory Tablet Containing Fenoprofen
The aim of this study was to formulate and evaluate a mouth - dissolving tablet of Fenoprofen, a nonsteroidal anti - inflammatory drug (NSAID), for rapid onset of action and improved patient compliance. Fenoprofen is known for its anti - inflammatory, analgesic, and antipyretic characteristics, but its conventional dosage forms have restrictions such as delayed onset of action and gastrointestinal irritation. In this work, we develop mouth - dissolving tablets using good excipients, add super disintegrants, make sure rapid disintegration and drug release. The tablets were analysed for various physicochemical variable such as disintegration time, drug content, in - vitro dissolution, and stability. The results shows that the improve formulation exhibited excellent disintegration and dissolution characteristics, with a significant upgrade in drug bioavailability correlate to standard formulations. The advanced mouth - dissolving tablets showed promise as a well - found alternative for delivering Fenoprofen in an efficient and patient - friendly manner.
Authors
- Shefali S. Verma (ORCID: https://orcid.org/0000-0001-5216-4670)
- Alka Verma
Publication Details
- Journal
- International Journal of Science and Research (IJSR)
- Published
- 2025-02-22
- DOI
- https://doi.org/10.21275/sr25217135130
- Primary Topic
- Pharmacological Effects of Natural Compounds
- Type
- article
- Field-Weighted Citation Impact
- 0.00