Camellia Tea Saponin Ameliorates 5–Fluorouracil-Induced Damage of HaCaT Cells by Regulating Ferroptosis and Inflammation
The insights of this work have identified biochemical mechanisms using tea saponin extract to protect against 5-FU-induced keratinocyte ferroptosis and inflammation. This study highlights the promising adjunctive potential of tea saponin in the mitigation and management of chemotherapy-induced mucositis.
Authors
- Somdet Srichairatanakool (ORCID: https://orcid.org/0000-0002-5706-8781)
- Haobo Ge (ORCID: https://orcid.org/0000-0002-8178-5369)
- Pimpisid Koonyosying (ORCID: https://orcid.org/0000-0002-6119-7009)
- Charareh Pourzand (ORCID: https://orcid.org/0000-0002-9046-1155)
- Narisara Paradee (ORCID: https://orcid.org/0000-0001-5863-2404)
- Sittiruk Roytrakul (ORCID: https://orcid.org/0000-0003-3696-8390)
- Tanrada Likitsatian
Institutions
- National Science and Technology Development Agency (TH)
- Chiang Mai University (TH)
- University of Bath (GB)
- National Center for Genetic Engineering and Biotechnology (TH)
Publication Details
- Journal
- Nutrients
- Published
- 2025-02-21
- DOI
- https://doi.org/10.3390/nu17050764
- Citations
- 5
- Primary Topic
- Ferroptosis and cancer prognosis
- Type
- article
- Field-Weighted Citation Impact
- 7.59
Funders
- Chiang Mai University