Development and refinement of the Clinical Global Impression of Improvement for Non-seizure Symptoms measure in Dravet syndrome and Lennox-Gastaut syndrome
This CGI-I Non-seizure Symptoms measure represents relevant non-seizure outcomes considered important to individuals with DS or LGS and their families. The systematic development and refinement approach presented here supports its use in DS and LGS clinical trials.
Authors
- Mahnaz Asgharnejad (ORCID: https://orcid.org/0000-0001-8060-2148)
- Drishti Shah (ORCID: https://orcid.org/0000-0002-5866-7743)
- Arturo Benitez (ORCID: https://orcid.org/0000-0001-6023-9871)
- Tara L. Symonds (ORCID: https://orcid.org/0000-0001-9145-5753)
- Lara Sams
- Alise Nacson (ORCID: https://orcid.org/0009-0004-9532-4274)
- Sophie L. Hughes
- J. Scott Andrews (ORCID: https://orcid.org/0009-0001-5516-7719)
Institutions
- Health Outcomes Solutions (United States) (US)
- Takeda (United States) (US)
- Takeda (Japan) (JP)
Publication Details
- Journal
- Journal of Patient-Reported Outcomes
- Published
- 2025-02-21
- DOI
- https://doi.org/10.1186/s41687-024-00829-2
- Citations
- 3
- Primary Topic
- Epilepsy research and treatment
- Type
- article
- Field-Weighted Citation Impact
- 4.41