Experimental efficacy of vaccination of weaned piglets with a modified-live commercial PRRS virus vaccine against the challenge with a Spanish highly virulent PRRSV-1 strain
In the present trial, vaccination resulted in improved clinical course, better weight gain and reduced viremia. At the peak of the infection, lung lesions were reduced in most animals although some individuals still had extensive pneumonia. In summary, vaccination was shown to provide partial but significant protection against the highly virulent R1 strain.
Authors
- L. Aguirre (ORCID: https://orcid.org/0000-0002-1660-4031)
- Martı́ Cortey (ORCID: https://orcid.org/0000-0003-1126-3423)
- Hepzibar Clilverd (ORCID: https://orcid.org/0000-0002-4309-7506)
- Jaime Gómez-Laguna (ORCID: https://orcid.org/0000-0002-1787-5642)
- Miguel Marcos (ORCID: https://orcid.org/0000-0003-1269-4487)
- José María Sánchez‐Carvajal (ORCID: https://orcid.org/0000-0003-0852-3765)
- Enric Mateu (ORCID: https://orcid.org/0000-0003-2715-6032)
- Rut Menjón (ORCID: https://orcid.org/0000-0002-1457-1758)
- Shannon Berg
- María S. Jiménez (ORCID: https://orcid.org/0000-0002-8460-6020)
- I. Domingo-Carreño
Institutions
- Universitat Autònoma de Barcelona (ES)
- MSD (Germany) (DE)
- University of Córdoba (ES)
Publication Details
- Journal
- Porcine Health Management
- Published
- 2025-02-21
- DOI
- https://doi.org/10.1186/s40813-025-00423-y
- Citations
- 4
- Primary Topic
- Animal Virus Infections Studies
- Type
- article
- Field-Weighted Citation Impact
- 4.77