Exploring the therapeutic potential of marjoram (Origanum majorana L.) in polycystic ovary syndrome: insights from serum metabolomics, network pharmacology and experimental validation
This study reveals that marjoram contains a diverse range of active compounds that can modulate crucial biochemical and histological markers related to PCOS. By combining serum pharmacochemistry with network pharmacology, the research highlights marjoram's potential as a natural supplement to help alleviate PCOS symptoms and slow the syndrome's progression. These findings support further investigation into marjoram's role as a complementary therapy for managing PCOS.
Authors
- Naglaa M. Ammar (ORCID: https://orcid.org/0000-0001-5798-6833)
- Aliaa M. Elfiky
- Amira R. Khattab
- Reham S. Ibrahim (ORCID: https://orcid.org/0000-0002-8208-5014)
- Eman Shawky (ORCID: https://orcid.org/0000-0003-0089-9629)
- Mai O. Kadry (ORCID: https://orcid.org/0000-0002-3920-6263)
Institutions
- Egyptian Government (EG)
- Arab Academy for Science, Technology, and Maritime Transport (EG)
- Alexandria University (EG)
Publication Details
- Journal
- BMC Complementary Medicine and Therapies
- Published
- 2025-02-21
- DOI
- https://doi.org/10.1186/s12906-025-04774-5
- Citations
- 6
- Primary Topic
- Ovarian function and disorders
- Type
- article
- Field-Weighted Citation Impact
- 10.19
Funders
- Science and Technology Development Fund
- Alexandria University