Incidence trends of early-onset breast cancer by lifestyle risk factors
The increase in early-onset breast cancer incidence was highest among women aged 40-49 who were overweight, currently smoking, or moderately physically active, while no change by risk factors was found in women under 40 years of age. Our findings suggest a different type of cancer process in young adults and highlight the importance of lifestyle risk factors in the incidence of EOBC.
Authors
- Karri Seppä (ORCID: https://orcid.org/0000-0002-3847-8814)
- Heidi Ryynänen
- Johan G. Eriksson (ORCID: https://orcid.org/0000-0002-2516-2060)
- Jasmiina Rantala (ORCID: https://orcid.org/0000-0001-5821-2944)
- Janne Pitkäniemi (ORCID: https://orcid.org/0000-0001-9879-6673)
- Sirpa Heinävaara (ORCID: https://orcid.org/0000-0002-8308-9922)
- Sanna Heikkinen (ORCID: https://orcid.org/0000-0001-9995-5605)
- Satu Männistö (ORCID: https://orcid.org/0000-0002-8668-3046)
- Maarit A. Laaksonen (ORCID: https://orcid.org/0000-0002-3676-0787)
- Paul Knekt (ORCID: https://orcid.org/0000-0002-2648-1338)
- Tommi Härkänen (ORCID: https://orcid.org/0000-0002-4577-1808)
- Pekka Jousilahti (ORCID: https://orcid.org/0000-0001-7190-0979)
- Nea Malila
- Ossi Rahkonen (ORCID: https://orcid.org/0000-0002-7202-3274)
- Eero Mäkinen
Institutions
- Agency for Science, Technology and Research (SG)
- The University of Sydney (AU)
- University of Helsinki (FI)
- National University of Singapore (SG)
- Tampere University (FI)
- Helsinki University Hospital (FI)
- Finnish Institute for Health and Welfare (FI)
- Finnish Cancer Registry (FI)
- Singapore Institute for Clinical Sciences (SG)
- Folkhälsans Forskningscentrum (FI)
Publication Details
- Journal
- BMC Cancer
- Published
- 2025-02-21
- DOI
- https://doi.org/10.1186/s12885-025-13730-y
- Citations
- 7
- Primary Topic
- Cancer Risks and Factors
- Type
- article
- Field-Weighted Citation Impact
- 7.32
Funders
- Helsingin Yliopisto