Mettl3-Mediated N6-Methyladenosine Modification Mitigates Ganglion Cell Loss and Retinal Dysfunction in Retinal Ischemia–Reperfusion Injury by Inhibiting FoxO1-Mediated Autophagy
Mettl3-mediated m6A modification mitigates RGC loss and retinal electrophysiologic dysfunction by inhibiting FoxO1-mediated autophagy in RIR injury.
Authors
- Lingyi Ouyang
- Jiazhen Feng
- Yiqiao Xing (ORCID: https://orcid.org/0000-0003-4482-3319)
- Tao He (ORCID: https://orcid.org/0000-0002-0317-7093)
- Feiyan Zhu (ORCID: https://orcid.org/0000-0001-9573-8478)
- Yiji Pan
Institutions
- Wuhan University (CN)
- Renmin Hospital of Wuhan University (CN)
Publication Details
- Journal
- Investigative Ophthalmology & Visual Science
- Published
- 2025-02-21
- DOI
- https://doi.org/10.1167/iovs.66.2.58
- Citations
- 8
- Primary Topic
- Autophagy in Disease and Therapy
- Type
- article
- Field-Weighted Citation Impact
- 10.83
Funders
- National Natural Science Foundation of China