Hyaluronic Acid-Based Therapy for Alleviating Early Lipid Peroxidation in Peripheral Nerve Compression Injury Repair
Early HA intervention modulates lipid peroxidation and oxidative stress via the HA/CD44 axis, establishing a supportive microenvironment for peripheral nerve regeneration and functional recovery. These findings underscore the potential of HA-based strategies to curb early lipid peroxidation, thereby expediting nerve repair and accelerating regeneration.
Authors
- Zhongyang Liu (ORCID: https://orcid.org/0000-0002-3371-2392)
- Cui Wang (ORCID: https://orcid.org/0000-0002-1610-2541)
- Yi Gao (ORCID: https://orcid.org/0000-0002-5996-3288)
- Rui Ma (ORCID: https://orcid.org/0000-0002-0592-8583)
- Chuyang Zeng
- Zhiqiang Liu (ORCID: https://orcid.org/0000-0002-0677-8097)
- Weidong Zhang (ORCID: https://orcid.org/0000-0002-7384-2490)
- Meng Li (ORCID: https://orcid.org/0000-0002-8348-6768)
- Xiaomeng Ren
- Xiaowen Xing
- Longbo Du
Institutions
- Beijing Institute of Education (CN)
- Chinese PLA General Hospital (CN)
- Chinese Institute for Brain Research (CN)
- Chinese People's Armed Police General Hospital (CN)
- Institute of Basic Medical Sciences of the Chinese Academy of Medical Sciences
Publication Details
- Journal
- World Neurosurgery
- Published
- 2025-02-21
- DOI
- https://doi.org/10.1016/j.wneu.2025.123818
- Citations
- 2
- Primary Topic
- Nerve injury and regeneration
- Type
- article
- Field-Weighted Citation Impact
- 1.82