Enhanced efficacy of immune checkpoint inhibitors by folate-targeted multifunctional drug through synergistic therapy inducing ferroptosis and immunogenic cell death in bladder cancer
DIFP-FA integrates SDT/CDT with chemotherapy to induce ferroptosis and ICD, efficiently eradicating tumors and activating the immune response, thereby enhancing the efficacy of ICB therapy.
Authors
- Hui Ding (ORCID: https://orcid.org/0000-0001-7087-9629)
- Hanzhang Wang (ORCID: https://orcid.org/0000-0002-8370-2061)
- Baodui Wang (ORCID: https://orcid.org/0000-0003-1600-6557)
- Junqiang Tian (ORCID: https://orcid.org/0000-0002-4529-4650)
- Enguang Yang (ORCID: https://orcid.org/0000-0002-9028-8065)
- Guangrui Fan (ORCID: https://orcid.org/0000-0002-0865-8080)
- Liang Cheng (ORCID: https://orcid.org/0000-0002-7270-5398)
- Zhiping Wang (ORCID: https://orcid.org/0000-0002-8140-591X)
- Yuanfeng Zhang (ORCID: https://orcid.org/0000-0002-5833-3460)
- Yibo Shi (ORCID: https://orcid.org/0000-0003-1523-6801)
- Tianzhi Hao
Institutions
- Lanzhou University of Technology (CN)
- Brown University (US)
- Lanzhou University Second Hospital (CN)
- Lanzhou University (CN)
Publication Details
- Journal
- Materials Today Bio
- Published
- 2025-02-21
- DOI
- https://doi.org/10.1016/j.mtbio.2025.101584
- Citations
- 8
- Primary Topic
- Ferroptosis and cancer prognosis
- Type
- article
- Field-Weighted Citation Impact
- 12.15