The effect of extracellular vesicles derived from oral squamous cell carcinoma on the metabolic profile of oral fibroblasts
The metabolic pathways of glycolysis, citric acid cycle, and amino acid metabolism were enriched, suggesting that OSCC EVs cause phenotype switch in NOFs that may contribute to acquiring a pro-tumorigenic phenotype.
Authors
- Anni I. Nieminen (ORCID: https://orcid.org/0000-0001-8999-6040)
- Dipak Sapkota (ORCID: https://orcid.org/0000-0003-0061-825X)
- Hilde Kanli Galtung (ORCID: https://orcid.org/0000-0001-7825-3540)
- Aleksandra Lipka (ORCID: https://orcid.org/0000-0003-0815-6635)
- Trude M. Haug (ORCID: https://orcid.org/0000-0003-3776-5077)
- Tine M. Søland (ORCID: https://orcid.org/0000-0003-1687-3247)
Institutions
- University of Helsinki (FI)
- University of Oslo (NO)
- Finland University (FI)
- Institute for Molecular Medicine Finland (FI)
Publication Details
- Journal
- Frontiers in Molecular Biosciences
- Published
- 2025-02-21
- DOI
- https://doi.org/10.3389/fmolb.2025.1492282
- Citations
- 2
- Primary Topic
- Extracellular vesicles in disease
- Type
- article
- Field-Weighted Citation Impact
- 1.61