A simple and effective screening strategy for early multiple system atrophy diagnosis and α-Synuclein forms in erythrocytes
Combining PVR urine volume and ΔSBP (at 1 and 3 min) is an easily accessible and effective method for distinguishing possible MSA from early-stage PD. This combination should be considered for routine assessment in Parkinsonism. Distinct α-Syn forms distribution in erythrocytes could be considered as a useful biomarker for differential diagnosis.
Authors
- Ying Jiang (ORCID: https://orcid.org/0000-0001-9800-6432)
- Qing Guan (ORCID: https://orcid.org/0000-0003-0383-2665)
- Yixuan Yin
- Jianing Jin (ORCID: https://orcid.org/0000-0002-2960-783X)
- Tao Feng (ORCID: https://orcid.org/0000-0002-0378-7764)
- Ying‐shan Piao
- Yang Gao (ORCID: https://orcid.org/0009-0007-3377-1695)
- Lian Tang (ORCID: https://orcid.org/0000-0002-8059-8166)
- Zhan Wang (ORCID: https://orcid.org/0009-0000-6968-7638)
Institutions
- Qingdao University (CN)
- Capital Medical University (CN)
- Beijing Tian Tan Hospital (CN)
- National Clinical Research Center for Digestive Diseases (CN)
- Affiliated Hospital of Qingdao University (CN)
Publication Details
- Journal
- Frontiers in Aging Neuroscience
- Published
- 2025-02-21
- DOI
- https://doi.org/10.3389/fnagi.2025.1533504
- Citations
- 1
- Primary Topic
- Parkinson's Disease Mechanisms and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 1.39
Funders
- National Natural Science Foundation of China