Deciphering the association between the Life’s Essential 8 and infertility: insights into depression, inflammation, and metabolic mediation

Higher LE8 scores, indicating better cardiovascular health, are associated with lower depression scores and reduced levels of SII and UA. These factors collectively contribute to a lower risk of infertility in women. Targeted interventions aimed at enhancing cardiovascular health may potentially mitigate infertility risk through these pathways.

Authors

Publication Details

Journal
Frontiers in Endocrinology
Published
2025-02-21
DOI
https://doi.org/10.3389/fendo.2025.1451030
Citations
2
Primary Topic
Birth, Development, and Health
Type
article
Field-Weighted Citation Impact
6.99
Controls
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article

Deciphering the association between the Life’s Essential 8 and infertility: insights into depression, inflammation, and metabolic mediation

Shichao Cui, Weibing Qin, Li Li, Wensheng Liu et al.
2 citations
Frontiers in Endocrinology
Birth, Development, and Health
6.99
article

Deciphering the association between the Life’s Essential 8 and infertility: insights into depression, inflammation, and metabolic mediation

Shichao Cui, Weibing Qin, Li Li, Wensheng Liu, Xingming Zhong
article en
2 citations

Abstract

Higher LE8 scores, indicating better cardiovascular health, are associated with lower depression scores and reduced levels of SII and UA. These factors collectively contribute to a lower risk of infertility in women. Targeted interventions aimed at enhancing cardiovascular health may potentially mitigate infertility risk through these pathways.

Frontiers in EndocrinologyVol. 16
Openalex Percentile: Top 5%
Birth, Development, and Health
6.99
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